![]() This information should be incorporated into the counseling process regarding the risks and benefits of endometrial sampling. The rate of significant abnormal endometrial pathology was 4% (23 cases) including 19 cases of endometrial hyperplasia without atypia (3.3%), and 4 cases of endometrial cancer (0.7%).Ĭonclusion: The rate of significant abnormal endometrial pathology in premenopausal women at low risk for endometrial hyperplasia or endometrial cancer presenting with AUB was very low. The pathology demonstrated benign in most cases (96%). Results: During the study period, 644 subjects were recruited, 557 of whom had adequate endometrial tissue for histopathology study. Data regarding baseline characteristics were collected, and histopathology reports were reviewed. Nulliparous, obesity, diabetes mellitus, polycystic ovary syndrome, chronic anovulation, infertility, tamoxifen therapy and/or a family history of uterine, ovarian, breast and colon cancer were excluded. The inclusion criteria were premenopausal women, 35– 50 years, presenting with AUB, low risk for endometrial hyperplasia or endometrial cancer, and having undergone endometrial sampling or uterine curettage. ![]() Patients and Methods: This descriptive study was conducted from Januto March 31, 2019. Pattarawadee Sattanakho, 1 Pilaiwan Kleebkaow, 1 Ussanee Sangkomkumhang, 2 Sukjai Booranabunyat, 3 Pranom Buppasiri 1ġDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2Department of Obstetrics and Gynecology, Khon Kaen Regional Hospital, Khon Kaen, Khon Kaen Province, Thailand 3Department of Obstetrics and Gynecology, Mahasarakham Hospital, Mahasarakham Province, Thailandĭepartment of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailandīackground and Objectives: To determine the rate of significant endometrial abnormalities in premenopausal women at low risk for endometrial hyperplasia and cancer presenting with abnormal uterine bleeding (AUB). ![]()
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